A new estimate published in The Lancet Journal suggests that respiratory syncytial virus (RSV) is responsible for more than 100,000 deaths among children under the age of five worldwide in 2019 due to respiratory infections. According to scientists, RSV is the most common cause of acute lower respiratory infections in young children.
This is the first study to examine the understanding of RSV disease in narrow age brackets. The study further revealed that in 2019, there were more than 45,000 deaths among children under six months of age, one in five worldwide RSV occurred within this age group.
“Our updated estimates indicate that babies aged six months or younger are particularly at risk, especially due to the relaxation of the Covid-19 restriction worldwide and most infants born in the last two years have never been exposed to RSV (and) therefore no resistance to the virus.” No power). With so many RSV vaccine candidates in the pipeline, our estimates by narrow age limits help identify groups that should be prioritized, including pregnant women, “said Harish Nair, University of Edinburgh co-author and co-author of the report.
According to the report, the results of the study are largely consistent with earlier estimates from a 2015 survey, which put the annual number of RSV cases among five-year-olds at 3.3 million, resulting in a total of 1,18,200 deaths. Also in 2019, 3.3 million RSV-related acute lower respiratory infections occurred among children under five, resulting in 26,300 hospital deaths, and 1,01,400 deaths responsible for RSV. This age limit is responsible for 2% of annual deaths due to any cause.
Meanwhile, for babies under six months of age, there were 66 million RSV-related acute lower respiratory infections worldwide in 2019, with 13,300 hospital deaths, and 45,700 overall deaths accounting for RSV – 2.1 percent of annual deaths for any reason.
According to the report, there were 53 (5.3 percent) incidence rates per 1,000 children per year in India and an estimated 61,86,500 episodes of RSV-related acute lower respiratory infections among children under five years of age.
Moreover, only 26 percent of RSV-related deaths worldwide occur in a single hospital. This is especially evident in low- and middle-income countries, where the hospital-mortality rate for children under five is 1.4 percent, compared to 0.1 percent in high-income countries. Overall, 97 percent of RSV deaths among children under five occurred in low- and middle-income countries.